ABO incompatibility with delayed hemolytic transfusion reaction Save
ICD-10 code: T80.311
Chapter: Injury, poisoning and certain other consequences of external causes
Understanding ABO Incompatibility with Delayed Hemolytic Transfusion Reaction
ABO incompatibility is a condition where a person's blood type is incompatible with the type of blood they receive during a transfusion. This can lead to a delayed hemolytic transfusion reaction (DHTR), a serious complication that can occur within a few days to weeks after a transfusion.
DHTR occurs when the body's immune system attacks the transfused red blood cells (RBCs), leading to their destruction. This can cause symptoms such as fever, chills, jaundice, anemia, and kidney failure. DHTR is a rare but potentially life-threatening complication of blood transfusions.
Causes of ABO Incompatibility
ABO incompatibility occurs when a person receives blood with a different ABO blood type than their own. There are four main blood types: A, B, AB, and O. Type A blood has A antigens on the surface of its RBCs, type B has B antigens, type AB has both A and B antigens, and type O has neither A nor B antigens.
If a person with type A blood receives type B blood, their body will recognize the B antigens as foreign and mount an immune response against them. This can lead to the destruction of the transfused RBCs and the development of DHTR.
Treatment of DHTR
The treatment of DHTR depends on the severity of the reaction. Mild cases may not require any treatment, while severe cases may require hospitalization and supportive care. This may include blood transfusions, medications to manage symptoms, and dialysis or other treatments for kidney failure.
The best way to prevent DHTR is to ensure that the blood type of the donor and recipient are compatible before a transfusion. This is done by performing ABO and Rh typing on both the donor and recipient blood, as well as cross-matching the two blood types to ensure compatibility.
Conclusion
ABO incompatibility with delayed hemolytic transfusion reaction is a rare but serious complication of blood transfusions. It occurs when a person's blood type is incompatible with the type of blood they receive, leading to the destruction of the transfused RBCs and the development of DHTR. The best way to prevent DHTR is to ensure that the blood types of the donor and recipient are compatible before a transfusion.
- ABO incompatibility occurs when a person receives blood with a different ABO blood type than their own.
- DHTR occurs when the body's immune system attacks the transfused red blood cells (RBCs), leading to their destruction.
- The treatment of DHTR
Diagnosis Codes for ABO incompatibility with delayed hemolytic transfusion reaction | T80.311