Acute promyelocytic leukemia digital illustration

Acute promyelocytic leukemia Save

ICD-10 code: C92.4

Chapter: Neoplasms

What is Acute Promyelocytic Leukemia?

Acute Promyelocytic Leukemia (APL) is a type of blood cancer that affects the white blood cells. It is a subtype of Acute Myeloid Leukemia (AML), which is a group of cancers that affect the bone marrow and blood.

APL is caused by a genetic mutation that affects the way white blood cells develop and mature. This mutation causes the cells to divide and grow abnormally, leading to the development of cancerous cells.

Symptoms of Acute Promyelocytic Leukemia

The symptoms of APL can vary from person to person, but some common symptoms include:

  1. Easy bruising or bleeding
  2. Fatigue or weakness
  3. Shortness of breath
  4. Fever or chills
  5. Unexplained weight loss
  6. Swollen lymph nodes
  7. Bone pain or tenderness

If you are experiencing any of these symptoms, it is important to see a doctor as soon as possible.

Treatment for Acute Promyelocytic Leukemia

The treatment for APL typically involves chemotherapy, which is a type of cancer treatment that uses drugs to kill cancer cells. In some cases, radiation therapy may also be used to target cancer cells in specific areas of the body.

In addition to chemotherapy and radiation therapy, some patients may also need a bone marrow transplant. This procedure involves replacing the patient's bone marrow with healthy bone marrow from a donor.


Acute Promyelocytic Leukemia is a serious condition that requires prompt diagnosis and treatment. If you are experiencing any symptoms of APL, it is important to see a doctor as soon as possible. With proper treatment, many patients are able to recover from APL and go on to live healthy, fulfilling lives.