Adverse effect of drugs affecting uric acid metabolism Save
ICD-10 code: T50.4X5
Chapter: Injury, poisoning and certain other consequences of external causes
Adverse Effect of Drugs Affecting Uric Acid Metabolism
Uric acid is a waste product that is produced when the body breaks down purines, which are found in many foods. Uric acid is normally removed from the body through urine, but if there is an excess of uric acid, it can build up in the body and cause health problems, such as gout or kidney stones.
There are several drugs that can affect uric acid metabolism, and their use can have adverse effects on the body. Some of these drugs are:
- Diuretics: These are drugs that increase the production of urine and are used to treat high blood pressure and edema. Diuretics can increase the concentration of uric acid in the blood, leading to gout attacks.
- Aspirin: This is a common pain reliever that can also affect uric acid metabolism. Aspirin can interfere with the excretion of uric acid, leading to an increase in its concentration in the blood.
- Cyclosporine: This drug is used to suppress the immune system and prevent organ rejection after transplant surgery. Cyclosporine can increase the concentration of uric acid in the blood, leading to gout attacks.
Other drugs that can affect uric acid metabolism include niacin, some chemotherapy drugs, and some medications used to treat HIV. If you are taking any of these drugs, it is important to talk to your doctor about the potential adverse effects on uric acid metabolism.
If you have a history of gout or kidney stones, or if you have high levels of uric acid in your blood, your doctor may recommend avoiding or limiting the use of these drugs. In some cases, your doctor may prescribe medications to help control uric acid levels in your body and prevent gout attacks or kidney stones.
In conclusion, drugs that affect uric acid metabolism can have adverse effects on the body, especially for those with a history of gout or kidney stones. It is important to talk to your doctor about any medications you are taking and their potential effects on uric acid metabolism.