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Adverse effect of other agents primarily affecting gastrointestinal system Save


ICD-10 code: T47.8X5

Chapter: Injury, poisoning and certain other consequences of external causes

Adverse Effect of Other Agents Primarily Affecting Gastrointestinal System

There are various medications that are primarily used to treat gastrointestinal disorders. However, some of these drugs can also have adverse effects on the gastrointestinal system. These effects can range from mild to severe and can sometimes lead to long-term complications.

Here are some of the common adverse effects of other agents primarily affecting the gastrointestinal system:

  1. Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

    NSAIDs are commonly used to relieve pain, inflammation, and fever. However, they can cause stomach irritation, ulcers, and bleeding. These side effects can occur even with short-term use of NSAIDs. Long-term use can increase the risk of developing serious gastrointestinal complications, such as perforation, obstruction, and hemorrhage.

  2. Corticosteroids

    Corticosteroids are used to treat a variety of conditions, including inflammatory bowel disease, autoimmune disorders, and allergies. However, they can cause stomach irritation, ulcers, and bleeding, especially when taken in high doses or for prolonged periods. Corticosteroids can also increase the risk of developing infections and osteoporosis.

  3. Antibiotics

    Antibiotics are used to treat bacterial infections in the digestive tract. However, they can also disrupt the balance of the gut microbiome, leading to diarrhea, bloating, and other gastrointestinal symptoms. In some cases, antibiotics can also cause a severe form of diarrhea called Clostridium difficile infection (CDI), which can be life-threatening.

  4. Proton Pump Inhibitors (PPIs)

    PPIs are commonly used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. However, they can cause side effects such as diarrhea, constipation, nausea, and abdominal pain. Long-term use of PPIs can also increase the risk of developing infections, kidney disease, and fractures.

If you experience any adverse effects while taking medications for gastrointestinal disorders, it is important to speak with your healthcare provider. They can help you determine the cause of your symptoms and recommend appropriate treatment options.

In conclusion, while medications can be helpful in treating gastrointestinal disorders, they can also have adverse effects on the digestive system. It is important to be aware of these potential side effects and to work closely with your healthcare provider to manage them effectively.