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Adverse effect of other antacids and anti-gastric-secretion drugs Save


ICD-10 code: T47.1X5

Chapter: Injury, poisoning and certain other consequences of external causes

Adverse Effects of Other Antacids and Anti-Gastric-Secretion Drugs

Antacids and anti-gastric-secretion drugs are commonly used to treat gastrointestinal disorders such as acid reflux, heartburn, and ulcers. While they can provide relief, these medications can also come with adverse effects that should not be ignored.

  1. Constipation or Diarrhea: Antacids that contain aluminum and magnesium can cause constipation, while those that contain magnesium can cause diarrhea. Anti-gastric-secretion drugs can also cause diarrhea, especially in high doses.
  2. Rebound Acid Production: Proton pump inhibitors (PPIs) are a type of anti-gastric-secretion drug that can cause rebound acid production. This means that once you stop taking the medication, your body may produce more acid than before, leading to more severe symptoms.
  3. Bone Loss: Long-term use of PPIs has been linked to an increased risk of bone loss and fractures. This is because these medications interfere with the absorption of calcium, which is essential for bone health.
  4. Malabsorption: Antacids and anti-gastric-secretion drugs can interfere with the absorption of other medications and nutrients. For example, PPIs can reduce the absorption of vitamin B12, which can lead to deficiencies.
  5. Increased Risk of Infections: Acid in the stomach helps to kill off harmful bacteria that may be ingested with food. By reducing acid production, anti-gastric-secretion drugs can increase the risk of infections such as pneumonia and Clostridium difficile (C. diff) colitis.

If you are taking antacids or anti-gastric-secretion drugs, it is important to be aware of these potential adverse effects and to talk to your doctor if you experience any symptoms. In some cases, alternative treatments or lifestyle changes may be recommended to manage your gastrointestinal symptoms without the use of medication.

Overall, while these medications can provide relief for gastrointestinal disorders, they can also come with adverse effects that should not be ignored. By being aware of these potential risks and talking to your doctor, you can make informed decisions about your treatment options.