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Adverse effect of phenothiazine antipsychotics and neuroleptics Save


ICD-10 code: T43.3X5

Chapter: Injury, poisoning and certain other consequences of external causes

Adverse Effect of Phenothiazine Antipsychotics and Neuroleptics

Phenothiazine antipsychotics and neuroleptics are commonly prescribed medications for the treatment of various mental health conditions, such as schizophrenia, bipolar disorder, and severe anxiety. However, these medications can have adverse effects on the body, which can range from mild to severe.

  1. Extrapyramidal Symptoms (EPS)
  2. EPS are movement disorders that can occur as a result of taking phenothiazine antipsychotics and neuroleptics. These symptoms can include tremors, muscle stiffness, akathisia (restlessness), and tardive dyskinesia (involuntary movements of the face and body).

  3. Cardiovascular Effects
  4. Phenothiazine antipsychotics and neuroleptics can also have an impact on the cardiovascular system. These medications can cause orthostatic hypotension, which is a sudden drop in blood pressure upon standing up. This can cause dizziness or even fainting.

  5. Metabolic Effects
  6. Phenothiazine antipsychotics and neuroleptics can cause metabolic effects such as weight gain, hyperglycemia, dyslipidemia, and insulin resistance. These effects can increase the risk of developing diabetes and cardiovascular disease.

  7. Neurological Effects
  8. Phenothiazine antipsychotics and neuroleptics can also have neurological effects. These medications can cause sedation, confusion, and cognitive impairment. Long-term use of these medications may also increase the risk of developing dementia.

It is important to note that not everyone who takes phenothiazine antipsychotics and neuroleptics will experience adverse effects. However, it is essential to discuss the potential risks and benefits of these medications with a doctor before starting treatment.

In conclusion, while phenothiazine antipsychotics and neuroleptics can be effective in treating mental health conditions, they can also have adverse effects on the body. Patients who are prescribed these medications should be closely monitored for any potential side effects and should discuss any concerns with their doctor.