Adverse effect of succinimides and oxazolidinediones digital illustration

Adverse effect of succinimides and oxazolidinediones Save


ICD-10 code: T42.2X5

Chapter: Injury, poisoning and certain other consequences of external causes

Adverse Effect of Succinimides and Oxazolidinediones

Succinimides and oxazolidinediones are anticonvulsant medications that are commonly used to treat epilepsy. They work by suppressing the electrical activity in the brain that causes seizures. These medications are effective in controlling seizures, but they also have some adverse effects that patients should be aware of.

  1. Psychiatric Symptoms: Both succinimides and oxazolidinediones can cause psychiatric symptoms such as depression, anxiety, and irritability. These symptoms may be more common in patients who have a history of psychiatric disorders.
  2. Birth Defects: Pregnant women who take succinimides or oxazolidinediones have an increased risk of giving birth to a baby with birth defects. These medications should be avoided during pregnancy unless the benefits outweigh the risks.
  3. Bone Loss: Long-term use of succinimides and oxazolidinediones can lead to a decrease in bone density, which increases the risk of fractures. Patients who take these medications should be monitored for bone loss and may need to take calcium and vitamin D supplements.
  4. Changes in Blood Counts: Both medications can cause changes in blood counts, such as a decrease in white blood cells, red blood cells, and platelets. Patients who take these medications should have their blood counts checked regularly.
  5. Allergic Reactions: Some patients may develop an allergic reaction to succinimides or oxazolidinediones, which can cause symptoms such as rash, itching, and difficulty breathing. Patients who experience these symptoms should seek medical attention immediately.

It is important for patients who take succinimides or oxazolidinediones to be aware of these potential adverse effects and to discuss any concerns with their healthcare provider. Patients should also report any unexpected symptoms or side effects to their healthcare provider. With proper monitoring and management, patients can safely use these medications to control their seizures.