Atresia of Vas Deferens, also known as congenital bilateral absence of the vas deferens (CBAVD), is a rare genetic condition that affects male fertility. It is caused by the absence or blockage of the vas deferens, the tubes that carry sperm from the testicles to the urethra during ejaculation.
CBAVD is usually diagnosed in men who have difficulty conceiving a child, and it is often associated with cystic fibrosis. In fact, up to 95% of men with CBAVD also have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which is responsible for producing a protein that helps regulate the transport of salt and water in and out of cells.
Men with CBAVD may not have any symptoms, as the absence or blockage of the vas deferens does not affect the production of sperm in the testicles. However, they may have difficulty conceiving a child, and may require assisted reproductive technologies such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to achieve a successful pregnancy.
Currently, there is no cure for CBAVD, but there are several treatment options available to help men with this condition conceive a child. These include:
Overall, while CBAVD can be a challenging condition to manage, there are several effective treatment options available to help men with this condition achieve their dream of having a child.