Chronic giant papillary conjunctivitis digital illustration

Chronic giant papillary conjunctivitis Save

ICD-10 code: H10.41

Chapter: Diseases of the eye and adnexia

What is Chronic Giant Papillary Conjunctivitis?

Chronic Giant Papillary Conjunctivitis (CGPC) is a condition in which the inner surface of the eyelids becomes inflamed, leading to itching, redness, and discomfort. This condition is often associated with the prolonged use of contact lenses or the presence of a foreign body, such as an artificial eye or a suture.

Symptoms of Chronic Giant Papillary Conjunctivitis

The symptoms of CGPC include itching, redness, tearing, mucous discharge, and discomfort. In severe cases, there may be a decrease in vision. The symptoms are usually more pronounced in the morning and improve throughout the day.

Treatment of Chronic Giant Papillary Conjunctivitis

The treatment of CGPC depends on the severity of the condition. In mild cases, the symptoms may be relieved by using artificial tears, avoiding the use of contact lenses, or switching to a different type of contact lens. In more severe cases, topical steroids or mast cell stabilizers may be necessary to reduce inflammation.

  1. Artificial Tears: Lubricating drops can relieve symptoms by reducing dryness and irritation.
  2. Avoidance of Contact Lenses: Discontinuing contact lens wear can help alleviate symptoms.
  3. Switching to a Different Type of Contact Lens: Some types of contact lenses may be less irritating than others.
  4. Topical Steroids: These medications can help reduce inflammation and relieve symptoms, but should only be used under the guidance of a healthcare professional.
  5. Mast Cell Stabilizers: These medications work by preventing the release of histamine, a chemical that causes inflammation and itching.
Prevention of Chronic Giant Papillary Conjunctivitis

CGPC can be prevented by following good eye hygiene practices, such as washing hands before handling contact lenses, cleaning lenses and cases regularly, and avoiding rubbing the eyes. It is also important to follow the recommended wearing and replacement schedule for contact lenses and to avoid sleeping in contact lenses.


Chronic Giant Papillary Conjunctivitis is a condition that can cause discomfort and irritation, especially for contact lens wearers. However, with proper treatment and prevention, it can be managed effectively. If you are experiencing symptoms of CGPC, it is important to seek medical attention from a healthcare professional.