Chronic myeloid leukemia, BCR/ABL-positive Chronic myeloid leukemia (CML) is a type of blood cancer that affects the bone marrow. It is characterized by the overproduction of white blood cells, which can crowd out other blood cells and make it difficult for the body to fight infections. CML is caused by a genetic mutation known as the BCR/ABL fusion gene, which causes the abnormal growth and division of white blood cells. Symptoms of CML can include fatigue, weight loss, night sweats, and abdominal pain. However, many people with CML may not experience any symptoms in the early stages of the disease. As the disease progresses, it can become more difficult to treat. Treatment for CML usually involves drugs that target the BCR/ABL fusion gene, such as imatinib, dasatinib, and nilotinib. These drugs can help to slow down the growth and division of white blood cells, and can even help to stop the progression of the disease in some cases. Other treatments for CML may include chemotherapy, radiation therapy, and stem cell transplantation. If you have been diagnosed with CML, it is important to work closely with your healthcare team to develop a treatment plan that is right for you. This may involve regular check-ups, blood tests, and other medical procedures to monitor your condition and ensure that your treatment is working effectively. In conclusion, chronic myeloid leukemia, BCR/ABL-positive is a serious disease that requires prompt and effective treatment. With proper medical care and support, however, many people with CML are able to manage their condition and live full and healthy lives. If you are experiencing any symptoms of CML, or if you have been diagnosed with the disease, be sure to speak with your healthcare provider as soon as possible to discuss your treatment options.