Chronic tubulo-interstitial nephritis Save
ICD-10 code: N11
Chapter: Diseases of the genitourinary system
Chronic Tubulo-Interstitial Nephritis: Causes, Symptoms, and Treatment
Chronic Tubulo-Interstitial Nephritis (CTIN), also known as Chronic Interstitial Nephritis, is a kidney disease that affects the tubules and interstitium of the kidney. This condition is characterized by inflammation and scarring of the kidney tissue, which can lead to kidney failure if left untreated.
- Causes
- Long-term use of certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or antibiotics
- Autoimmune disorders, such as lupus or vasculitis
- Chronic infections, such as pyelonephritis
- Exposure to toxins, such as heavy metals or solvents
- Genetic factors
- Symptoms
- Fatigue
- Nausea and vomiting
- Loss of appetite
- Weight loss
- Swelling in the legs and ankles
- High blood pressure
- Decreased urine output
- Blood in the urine
- Treatment
- Stopping the use of medications that may be causing the condition
- Treating underlying infections or autoimmune disorders
- Controlling high blood pressure and managing fluid and electrolyte balance
- Dialysis or kidney transplant in severe cases
CTIN can be caused by a variety of factors, including:
CTIN may not cause any symptoms in its early stages. As the disease progresses, the following symptoms may occur:
There is no cure for CTIN, but treatment can help manage symptoms and slow the progression of the disease. Treatment may include:
If you experience any of the symptoms listed above, it is important to consult a healthcare professional for an accurate diagnosis and appropriate treatment.