Diabetes mellitus is a chronic metabolic disorder that affects the body's ability to produce or use insulin. It is a leading cause of morbidity and mortality worldwide, with an estimated 463 million people living with the disease in 2019. While there are various causes of diabetes mellitus, drug or chemical-induced diabetes mellitus is a less common form of the disease.
When drug or chemical-induced diabetes mellitus occurs, it is usually due to the use of certain medications that can cause insulin resistance or damage to the pancreas. Some drugs that can cause diabetes mellitus include corticosteroids, thiazide diuretics, and antipsychotics.
Proliferative diabetic retinopathy (PDR) is a complication of diabetes mellitus that affects the eyes. It occurs when the blood vessels in the retina begin to grow abnormally, causing bleeding and scarring. PDR can lead to serious vision problems, including blindness, if left untreated.
Traction retinal detachment (TRD) is a type of retinal detachment that occurs when scar tissue pulls the retina away from the back of the eye. TRD can cause vision loss and requires prompt treatment to prevent permanent damage.
When PDR and TRD occur together in patients with drug or chemical-induced diabetes mellitus, it can create a challenging clinical situation. Treatment options for these patients may include laser photocoagulation or vitrectomy surgery.
It is important for healthcare providers to recognize the risk of drug or chemical-induced diabetes mellitus and to monitor patients who are taking medications that can cause the disease. Patients with diabetes mellitus should also receive regular eye exams to detect and treat complications like PDR and TRD before they cause permanent vision loss.
In conclusion, drug or chemical-induced diabetes mellitus with PDR and TRD not involving the macula is a complex clinical situation that requires
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