Diabetes mellitus (DM) is a chronic metabolic disorder characterized by high blood glucose levels. It is caused by the insufficient production or utilization of insulin, a hormone that regulates blood sugar levels. DM can lead to a variety of complications, including diabetic retinopathy (DR), a condition that affects the eyes.
DR is a leading cause of blindness in adults worldwide. It is caused by damage to the blood vessels in the retina, the light-sensitive tissue at the back of the eye. DR can cause vision loss and blindness if left untreated.
Drug or chemical-induced DM is a type of diabetes that is caused by the use of certain drugs or chemicals. Some medications, such as corticosteroids and antipsychotics, can cause DM by interfering with insulin production or utilization. Chemicals such as pesticides and herbicides can also cause DM by damaging the pancreas, the organ responsible for producing insulin.
Proliferative diabetic retinopathy (PDR) is a severe form of DR that occurs when new blood vessels grow in the retina. These blood vessels are weak and can leak blood and other fluids into the eye, causing vision loss and blindness. PDR can also lead to the formation of scar tissue, which can pull on the retina and cause it to detach from the back of the eye.
Macular edema is a common complication of DR that occurs when fluid accumulates in the macula, the central part of the retina responsible for sharp, clear vision. Macular edema can cause blurry, distorted vision and can worsen over time.
Treatment for drug or chemical-induced DM with PDR without macular edema is similar to that for other forms of DM with PDR. Treatment may include medications to control blood sugar levels, laser surgery to seal leaking blood vessels, and vitrectomy surgery to remove scar tissue and blood from the eye.
If you are taking medications or exposed to chemicals that may cause DM, it is important to monitor your blood sugar levels regularly and to report any symptoms of DM or DR to your healthcare provider.
Overall, drug or chemical-induced DM with PDR without macular edema is a serious condition that requires prompt diagnosis and treatment. With proper management, it is possible to prevent or delay the progression of DR and to