Granulomatous disorders of skin and subcutaneous tissue Save

Understanding Granulomatous Disorders of Skin and Subcutaneous Tissue

Granulomatous disorders of skin and subcutaneous tissue are a group of diseases that affect the skin and the tissues just beneath it. These disorders are characterized by the formation of granulomas, which are small, round nodules made up of immune cells, such as macrophages and lymphocytes.

The most common granulomatous disorders of skin and subcutaneous tissue include:

1. Sarcoidosis
2. Tuberculosis
3. Leprosy
4. Granuloma annulare
5. Wegener's granulomatosis

Sarcoidosis is a systemic disease that can affect multiple organs, including the skin and subcutaneous tissue. It is characterized by the formation of non-caseating granulomas, which are granulomas that do not contain necrotic tissue. The skin lesions in sarcoidosis can appear as papules, nodules, or plaques, and they may be red, purple, or brown in color.

Tuberculosis is a bacterial infection that can affect the lungs, but it can also affect the skin and subcutaneous tissue. Tuberculosis of the skin is also known as cutaneous tuberculosis, and it typically presents as a single, firm, painless nodule or ulcer. The skin lesion may be surrounded by a red, raised border, and it may discharge pus or blood.

Leprosy, also known as Hansen's disease, is a chronic bacterial infection that primarily affects the skin and nerves. The skin lesions in leprosy can appear as hypopigmented or erythematous patches, nodules, or plaques. Leprosy can also cause nerve damage, which can lead to sensory loss, muscle weakness, and deformities.

Granuloma annulare is a benign, self-limiting skin condition that is characterized by the formation of annular, flesh-colored or pinkish-red papules or plaques. The lesions are often located on the hands, feet, or ankles, and they may be itchy or tender.

Wegener's granulomatosis, also known as granulomatosis with polyangiitis, is a rare autoimmune disease that primarily affects the respiratory tract and kidneys. However, it can also affect the skin and subcutaneous tissue, causing nodules, ulcers, or purpura.

Granulomatous disorders of skin and subcutaneous tissue can be challenging to diagnose and treat. If you are experiencing skin lesions or other symptoms, it is important to seek medical attention promptly. Your healthcare provider can perform a thorough evaluation and recommend appropriate diagnostic tests