Malignant carcinoid tumors of the small intestine are relatively rare, accounting for only 1-2% of all gastrointestinal neoplasms. However, they are important to recognize and treat early, as they can cause significant morbidity and mortality if left untreated.
Carcinoid tumors are a type of neuroendocrine tumor that arises from neuroendocrine cells in various organs throughout the body. In the small intestine, they typically arise from the ileum and can present with a variety of symptoms, including abdominal pain, diarrhea, and weight loss.
Diagnosis of malignant carcinoid tumors of the small intestine can be challenging, as symptoms may be non-specific and imaging studies such as CT scans and MRIs may not always detect the tumor. Endoscopic evaluation, including upper endoscopy and colonoscopy, may be necessary to visualize the tumor and obtain a biopsy for diagnosis.
Treatment for malignant carcinoid tumors of the small intestine typically involves surgical resection of the tumor, which may be curative if the tumor is found early and has not spread to other organs. Chemotherapy and radiation therapy may also be used in conjunction with surgery in certain cases.
In summary, malignant carcinoid tumors of the small intestine are a rare but important type of gastrointestinal neoplasm that can cause significant morbidity and mortality if left untreated. Early diagnosis and treatment are key to improving outcomes for patients with this condition.