Rhesus isoimmunization is a condition that occurs when a pregnant woman has Rh-negative blood and her baby has Rh-positive blood. If the baby's blood enters the mother's bloodstream, her immune system may react by producing antibodies that can attack the baby's red blood cells. This condition can cause severe anemia and jaundice in the baby, and in severe cases, it can even be life-threatening. However, there are steps that can be taken to prevent or manage this condition.
One of the most effective ways to prevent rhesus isoimmunization is through the use of Rh immune globulin (RhIg). This medication is given to Rh-negative women during pregnancy and after delivery to prevent their immune systems from producing antibodies against Rh-positive blood. In women who have already developed antibodies, RhIg is not effective.
If a woman is already sensitized to Rh-positive blood, her healthcare provider may recommend fetal blood sampling. This procedure involves taking a small sample of blood from the baby to check for anemia and other complications. Fetal blood sampling can help healthcare providers determine the best course of treatment for the baby.
In severe cases of rhesus isoimmunization, intrauterine transfusion may be necessary. This procedure involves transfusing the baby with Rh-negative blood while still in the womb. Intrauterine transfusion is a highly specialized procedure that is only performed in specialized medical centers.
It is important for women who are Rh-negative to receive prenatal care and testing to monitor for rhesus isoimmunization. If you are Rh-negative, talk to your healthcare provider about your options for preventing or managing rhesus isoimmunization.
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