Mycosis fungoides digital illustration

Mycosis fungoides Save

ICD-10 code: C84.0

Chapter: Neoplasms

Mycosis Fungoides: Understanding Symptoms, Diagnosis, and Treatment

Mycosis fungoides is a rare type of non-Hodgkin's lymphoma that affects the skin. It is also known as Alibert-Bazin syndrome or granuloma fungoides. This condition is characterized by patches, plaques, and nodules on the skin that can be itchy, painful, and disfiguring. Mycosis fungoides is a slow-growing cancer that can develop over years or even decades.

The exact cause of mycosis fungoides is unknown, but it is believed to be related to abnormal T-cell activity. T-cells are a type of white blood cell that helps the body fight infections. In mycosis fungoides, T-cells become abnormal and start to attack healthy skin cells.


The symptoms of mycosis fungoides can vary depending on the stage of the disease. In the early stages, the symptoms may be mild and go unnoticed. However, as the disease progresses, the following symptoms may appear:

  1. Red, scaly patches on the skin
  2. Thick, raised plaques on the skin
  3. Lumps or nodules under the skin
  4. Itching, burning, or tingling sensations on the affected skin
  5. Ulcers or open sores on the skin that do not heal

Diagnosing mycosis fungoides can be difficult because the symptoms can be similar to other skin conditions. A dermatologist will usually perform a skin biopsy to confirm the diagnosis. During a skin biopsy, a small piece of skin is removed and examined under a microscope to look for abnormal T-cells.

If mycosis fungoides is diagnosed, further tests may be needed to determine the stage of the disease. These tests may include blood tests, imaging tests, and bone marrow biopsies.


The treatment for mycosis fungoides will depend on the stage of the disease and the severity of the symptoms. In the early stages, treatment may not be necessary, and the dermatologist may recommend monitoring the skin for any changes.

If the symptoms are more severe, treatment may include the following: