Default disease illustration

Osteonecrosis due to drugs, humerus Save


ICD-10 code: M87.12

Chapter: Diseases of the musculoskeletal system and connective tissue

Osteonecrosis due to drugs, humerus

Osteonecrosis, also known as avascular necrosis, is a condition that occurs when bone tissue dies due to a lack of blood supply. This can lead to pain, limited mobility, and even fractures. While osteonecrosis can happen in any bone in the body, it is most commonly found in the hip, knee, and shoulder joints.

One of the lesser-known causes of osteonecrosis is the use of certain medications. In particular, drugs known as bisphosphonates, which are commonly used to treat osteoporosis, have been linked to an increased risk of osteonecrosis in the jaw, known as ONJ. However, recent studies have also suggested a link between bisphosphonate use and osteonecrosis in the humerus, or upper arm bone.

While the exact mechanism behind this connection is not yet fully understood, it is thought that bisphosphonates may interfere with the body's natural bone remodeling process, leading to weakened bones that are more susceptible to osteonecrosis. Other drugs, such as corticosteroids and anticoagulants, have also been associated with an increased risk of osteonecrosis.

If you are taking any of these medications and experience sudden pain or limited mobility in your shoulder or upper arm, it is important to speak with your doctor. An early diagnosis and treatment can help prevent further damage and improve your chances of recovery.

  1. Common symptoms of osteonecrosis include:
    • Pain in the affected joint, which may be severe and worsen with activity
    • Stiffness and limited mobility
    • Cracking or popping sounds in the joint
    • Weakness in the affected area
  2. Diagnosis and treatment
  3. If you are experiencing any of these symptoms, your doctor may recommend imaging tests such as an X-ray, MRI, or CT scan to confirm a diagnosis of osteonecrosis. Treatment options may vary depending on the severity of the condition and may include medication to manage pain and inflammation, physical therapy, or surgery to remove damaged tissue or replace the affected joint.

  4. Prevention
  5. If you are taking medications that have been associated with an increased risk of osteonecrosis, it is important to discuss the potential risks and benefits with your doctor. You may also be advised to maintain a healthy lifestyle, including regular exercise and a balanced diet, to help keep your bones strong and reduce your risk of osteonecrosis.

In conclusion, while osteonecrosis due to drugs in the humerus is a relatively rare condition, it is important to be aware of the potential risks associated with certain medications.