Other non-ABO incompatibility reaction due to transfusion of blood or blood products Save

Other non-ABO incompatibility reaction due to transfusion of blood or blood products

Transfusion of blood or blood products is a common medical intervention that can save lives in emergencies or improve the health of patients with medical conditions. However, there are risks associated with transfusions, including the possibility of non-ABO incompatibility reactions.

Non-ABO incompatibility reactions occur when the recipient's immune system reacts to antigens in the transfused blood or blood products that are not part of the ABO blood group system. These reactions can be mild or severe, and in some cases, they can be life-threatening.

There are several types of non-ABO incompatibility reactions, including febrile non-hemolytic transfusion reactions, allergic reactions, transfusion-related acute lung injury, and transfusion-associated graft-versus-host disease.

1. Febrile non-hemolytic transfusion reactions (FNHTR) are the most common type of non-ABO incompatibility reaction. Symptoms include fever, chills, and rigors. These reactions are usually mild and self-limiting, but they can be distressing for patients.
2. Allergic reactions can occur when the recipient's immune system reacts to proteins in the transfused blood or blood products. Symptoms can include hives, itching, and wheezing. In severe cases, anaphylaxis can occur, which is a life-threatening allergic reaction.
3. Transfusion-related acute lung injury (TRALI) is a rare but serious reaction that can occur when transfused blood or blood products cause inflammation in the lungs. Symptoms include shortness of breath and low oxygen levels. TRALI can be fatal in some cases.
4. Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but potentially fatal reaction that can occur when transfused blood or blood products contain viable T-lymphocytes that attack the recipient's tissues. Symptoms can include rash, fever, and liver dysfunction. TA-GVHD can be prevented by irradiating the blood products before transfusion.

If you are going to receive a blood transfusion or blood products, it is important to discuss the risks and benefits with your healthcare provider. Your healthcare provider can help you understand the potential risks and take steps to minimize them. If you experience any symptoms after a transfusion, be sure to inform your healthcare provider immediately so that appropriate treatment can be provided.

In conclusion, non-ABO incompatibility reactions can occur after transfusion of blood or blood products. These reactions can be mild or severe, and in some cases, they can be life-threatening. It is important to be aware of the potential risks and to discuss them with your healthcare provider before