Pathological fractures are defined as fractures that occur in bones that have been weakened by an underlying disease or condition, such as cancer. Neoplastic disease, or cancer, can weaken bones and make them more susceptible to pathological fractures. The pelvis is a common site for pathological fractures in neoplastic disease due to its weight-bearing role in the body.
There are several types of neoplastic diseases that can lead to pathological fractures in the pelvis, including primary bone tumors, metastatic bone disease, and multiple myeloma. Primary bone tumors, such as osteosarcoma and chondrosarcoma, can weaken the bone and cause fractures. Metastatic bone disease, which occurs when cancer cells from other parts of the body spread to the bones, can also weaken the bone and cause fractures. Multiple myeloma, a cancer of the plasma cells in the bone marrow, can cause the bone to become weak and brittle, leading to fractures.
The symptoms of a pathological fracture in the pelvis can include pain, swelling, and difficulty walking or standing. Imaging tests, such as X-rays, CT scans, and MRI scans, can be used to diagnose a pathological fracture and determine the extent of the bone damage.
Treatment for a pathological fracture in the pelvis will depend on the underlying neoplastic disease and the extent of the fracture. In some cases, surgery may be necessary to stabilize the bone and prevent further damage. Radiation therapy may also be used to help strengthen the bone and reduce pain. In cases where the fracture is severe and the bone cannot be repaired, an artificial hip or other prosthetic may be necessary to restore mobility.
In conclusion, pathological fractures in neoplastic disease, pelvis can be a serious complication that can cause pain, disability, and loss of mobility. Early diagnosis and treatment are essential to prevent further damage and improve quality of life. If you are experiencing symptoms of a pathological fracture, such as pain or swelling in the pelvis, it is important to seek medical attention right away.