Pathological fractures are fractures that occur in bones that have been weakened by a disease process. Neoplastic diseases, or cancers that originate in bone or spread to the bone, are a common cause of pathological fractures. The tibia and fibula are two bones in the lower leg that are frequently affected by neoplastic disease and subsequent pathological fracture.
Neoplastic diseases such as multiple myeloma, osteosarcoma, and metastatic carcinoma can weaken the bones and lead to pathological fractures. These cancers can invade the bone tissue, causing damage and reducing bone density. As a result, the bones become more susceptible to fractures from even minor trauma.
Pain, swelling, and tenderness are common symptoms of a pathological fracture. The affected limb may also appear deformed or misaligned. In some cases, a pathological fracture may be the first indication of an underlying neoplastic disease.
Treatment for a pathological fracture in neoplastic disease depends on the type and extent of the underlying cancer. Surgery may be necessary to stabilize the bone and prevent further damage. Chemotherapy or radiation therapy may also be needed to target the cancer cells and reduce the risk of further fractures.
Preventing pathological fractures in neoplastic disease involves managing the underlying cancer and taking steps to maintain bone health. This may include regular exercise, a diet rich in calcium and vitamin D, and medications to increase bone density.
If you are experiencing symptoms of a pathological fracture in the tibia or fibula, it is important to seek medical attention promptly. An accurate diagnosis and appropriate treatment can help prevent further damage and improve your overall quality of life.
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