Poisoning by angiotensin-converting-enzyme inhibitors, intentional self-harm digital illustration

Poisoning by angiotensin-converting-enzyme inhibitors, intentional self-harm Save


ICD-10 code: T46.4X2

Chapter: Injury, poisoning and certain other consequences of external causes

Understanding Poisoning by Angiotensin-Converting-Enzyme Inhibitors in Cases of Intentional Self-Harm

Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a commonly prescribed medication for hypertension and heart failure. They work by blocking the conversion of angiotensin I to angiotensin II, which results in vasodilation and decreased blood pressure. However, in cases of intentional self-harm, ACE inhibitors can be used to cause harm to oneself.

ACE inhibitors can be extremely dangerous in cases of intentional overdose or poisoning. Symptoms of poisoning can include low blood pressure, dizziness, and fainting. In severe cases, it can result in shock, kidney failure, and even death. Therefore, it is important to understand the risks associated with ACE inhibitor poisoning in cases of intentional self-harm.

  1. Risk Factors: People who are at increased risk of intentional self-harm are more likely to abuse ACE inhibitors. This includes individuals with a history of mental illness, substance abuse, and previous suicide attempts.
  2. Symptoms: Symptoms of ACE inhibitor poisoning can include low blood pressure, dizziness, fainting, and fatigue. In severe cases, symptoms can progress to kidney failure, shock, and death.
  3. Treatment: Treatment for ACE inhibitor poisoning includes supportive care, such as IV fluids and monitoring of blood pressure and kidney function. In severe cases, dialysis may be necessary.
  4. Prevention: Prevention of ACE inhibitor poisoning involves careful prescription of the medication and monitoring of patients who are at increased risk of intentional self-harm. Healthcare providers should also educate patients about the risks associated with ACE inhibitor abuse.

In conclusion, poisoning by angiotensin-converting-enzyme inhibitors is a serious and potentially deadly consequence of intentional self-harm. Understanding the risks and symptoms associated with ACE inhibitor poisoning is essential for healthcare providers to provide appropriate care and prevent harm to their patients.