Poisoning by drugs affecting uric acid metabolism, undetermined digital illustration

Poisoning by drugs affecting uric acid metabolism, undetermined Save


ICD-10 code: T50.4X4

Chapter: Injury, poisoning and certain other consequences of external causes

Poisoning by drugs affecting uric acid metabolism, undetermined

Poisoning by drugs affecting uric acid metabolism is a serious medical condition that can lead to various health complications if left untreated. However, in some cases, the exact cause of the poisoning may be undetermined, making it difficult for medical professionals to provide targeted treatment.

Uric acid is a byproduct of purine metabolism in the body. When the body is unable to eliminate uric acid effectively, it can lead to a build-up of uric acid in the blood, resulting in hyperuricemia.

Some drugs can affect uric acid metabolism in the body, leading to a condition known as drug-induced hyperuricemia. This can happen if the drug interferes with the excretion of uric acid or increases its production. If the levels of uric acid in the blood become too high, it can lead to gout, kidney stones, and other complications.

  1. Common drugs that can cause hyperuricemia include:
    • Diuretics
    • Cyclosporine
    • Aspirin
    • Niacin
    • Levodopa
  2. Diagnosis of drug-induced hyperuricemia can be challenging, especially if the exact cause is unknown.
  3. Treatment for drug-induced hyperuricemia may involve discontinuing the use of the drug or reducing the dosage.
  4. In severe cases, medication to lower uric acid levels may be prescribed.

If the exact cause of poisoning by drugs affecting uric acid metabolism is undetermined, treatment may involve supportive care to manage symptoms and prevent complications. Patients may be advised to follow a low-purine diet and increase their fluid intake to help flush out excess uric acid from the body.

It is important to seek medical attention if you experience symptoms of hyperuricemia, such as joint pain, swelling, and redness. With prompt and appropriate treatment, most cases of drug-induced hyperuricemia can be managed effectively, and patients can go on to live healthy, productive lives.