Glucocorticoids and synthetic analogues are commonly used for their anti-inflammatory and immunosuppressive properties, but they can also be abused for their psychoactive effects. Poisoning by these substances is a serious concern, particularly in cases of intentional self-harm.
Symptoms of glucocorticoid poisoning can vary depending on the dose and duration of exposure. Common symptoms include weight gain, mood swings, insomnia, and increased blood pressure. In severe cases, glucocorticoid poisoning can lead to adrenal suppression and even death.
Treatment for glucocorticoid poisoning typically involves supportive care, such as fluid resuscitation and electrolyte replacement. In cases of intentional self-harm, psychiatric evaluation and counseling may also be necessary.
Preventing glucocorticoid poisoning requires proper prescribing and monitoring of these medications. Patients should be informed of the potential risks and side effects associated with glucocorticoid use, and healthcare providers should carefully monitor patients for signs of abuse or misuse.
In addition to intentional self-harm, glucocorticoid poisoning can also occur through accidental overdose or improper use. Patients should be instructed to take medications as directed and to never exceed the recommended dose without medical supervision.
Overall, poisoning by glucocorticoids and synthetic analogues is a serious concern, particularly in cases of intentional self-harm. Proper prescribing and monitoring of these medications, along with patient education and supportive care, can help prevent and manage these potentially life-threatening situations.