Poisoning by monoamine-oxidase-inhibitor antidepressants, accidental (unintentional) digital illustration

Poisoning by monoamine-oxidase-inhibitor antidepressants, accidental (unintentional) Save


ICD-10 code: T43.1X1

Chapter: Injury, poisoning and certain other consequences of external causes

What is Poisoning by Monoamine-Oxidase-Inhibitor Antidepressants?

Poisoning by monoamine-oxidase-inhibitor (MAOI) antidepressants can occur when someone accidentally takes too much of the medication. MAOIs are a type of antidepressant that work by blocking the activity of an enzyme called monoamine oxidase, which breaks down neurotransmitters such as serotonin and dopamine. By blocking this enzyme, MAOIs increase the levels of these neurotransmitters in the brain, which can improve mood and alleviate symptoms of depression.

Symptoms of MAOI Poisoning

When someone takes too much of an MAOI antidepressant, it can lead to several symptoms. These symptoms may include:

  1. Headache
  2. Nausea and vomiting
  3. High blood pressure
  4. Fast heart rate
  5. Confusion
  6. Seizures
  7. Coma

If you or someone you know is experiencing these symptoms and has recently taken an MAOI antidepressant, it is important to seek medical attention immediately. MAOI poisoning can be life-threatening if left untreated.

Treatment for MAOI Poisoning

If someone has taken too much of an MAOI antidepressant, treatment may involve hospitalization and supportive care. This may include:

  • Monitoring of vital signs, such as blood pressure and heart rate
  • Administration of medications to control blood pressure and heart rate
  • Seizure management
  • Activated charcoal or gastric lavage to remove the medication from the stomach
  • Supportive care, such as oxygen therapy or intravenous fluids

It is important to remember that MAOIs can interact with many other medications and foods, which can increase the risk of toxicity. It is important to talk to your doctor or pharmacist before taking any new medications or supplements while on an MAOI antidepressant.

Conclusion

Poisoning by monoamine-oxidase-inhibitor (MAOI) antidepressants can occur when someone accidentally takes too much of the medication. Symptoms may include headache, nausea and vomiting, high blood pressure, fast heart rate, confusion, seizures, and coma. Treatment may involve hospitalization and supportive care. To prevent MAOI poisoning, it is important to talk to your doctor or pharmacist before taking any new medications or supplements while on an MAOI antidepressant.