Poisoning by other antihypertensive drugs, assault digital illustration

Poisoning by other antihypertensive drugs, assault Save


ICD-10 code: T46.5X3

Chapter: Injury, poisoning and certain other consequences of external causes

Poisoning by Other Antihypertensive Drugs: Assault

Poisoning by antihypertensive drugs is a serious situation that requires immediate medical attention. Assault by poisoning is one of the leading causes of poisoning deaths worldwide, and antihypertensive drugs are a common agent used for this purpose.

Antihypertensive drugs are used to lower high blood pressure and are commonly prescribed to patients with hypertension. However, when taken in large doses or in combination with other drugs, they can be toxic and even life-threatening.

The most common antihypertensive drugs involved in poisoning cases are calcium channel blockers, beta-blockers, and angiotensin-converting enzyme (ACE) inhibitors. These drugs can cause a variety of symptoms, including dizziness, nausea, vomiting, and a decreased heart rate. In severe cases, they can cause seizures, coma, or even death.

  1. Calcium channel blockers: These drugs block the entry of calcium ions into heart muscle cells, which causes the heart to beat more slowly and with less force. In high doses, they can cause hypotension, bradycardia, and cardiac arrest.
  2. Beta-blockers: These drugs block the effects of adrenaline, which decreases heart rate and blood pressure. In high doses, they can cause hypotension, bradycardia, and heart failure.
  3. ACE inhibitors: These drugs block the conversion of angiotensin I to angiotensin II, which causes blood vessels to dilate and lower blood pressure. In high doses, they can cause hypotension, dizziness, and renal failure.

If you suspect that someone has been poisoned by antihypertensive drugs, it is important to seek medical attention immediately. The first step in treating antihypertensive drug poisoning is to stabilize the patient's vital signs, such as heart rate and blood pressure. This may involve administering intravenous fluids or medications to increase blood pressure.

In severe cases, hospitalization may be necessary for further treatment and monitoring. This may include hemodialysis to remove the drug from the patient's bloodstream or the administration of an antidote, such as glucagon or calcium.

In conclusion, poisoning by antihypertensive drugs is a serious and potentially life-threatening situation. If you suspect that someone has been poisoned by these drugs, seek medical attention immediately to ensure the best possible outcome.