Poisoning by selective serotonin reuptake inhibitors, intentional self-harm digital illustration

Poisoning by selective serotonin reuptake inhibitors, intentional self-harm Save


ICD-10 code: T43.222

Chapter: Injury, poisoning and certain other consequences of external causes

Poisoning by Selective Serotonin Reuptake Inhibitors and Intentional Self-Harm: Understanding the Link

Selective Serotonin Reuptake Inhibitors (SSRIs) are a class of antidepressant medications that are widely used in the treatment of depression, anxiety, and other mental health conditions. While SSRIs are generally considered safe and effective, they can be dangerous if taken in excessive amounts or in combination with certain other medications. In fact, intentional self-harm by poisoning with SSRIs is a growing concern in the mental health community.

According to a study published in the Journal of Affective Disorders, intentional self-harm by poisoning with SSRIs is becoming more common. The study found that between 2000 and 2014, there was a significant increase in the number of hospital admissions for intentional self-harm by poisoning with SSRIs. The study also found that the risk of intentional self-harm by poisoning with SSRIs was highest among young adults and women.

So, why are SSRIs associated with intentional self-harm? One theory is that SSRIs can cause a condition known as akathisia, which is a feeling of inner restlessness and agitation. Akathisia can be extremely uncomfortable and can lead to suicidal thoughts and behaviors. In addition, SSRIs can also cause other side effects such as insomnia, anxiety, and agitation, which can contribute to suicidal behavior.

It is important to note that not everyone who takes SSRIs will experience these side effects, and many people find SSRIs to be a helpful and life-saving medication. However, it is crucial for healthcare providers to monitor patients who are taking SSRIs for signs of akathisia and other side effects. Patients who are experiencing these side effects should be closely monitored and may need to have their medication adjusted or changed.

  1. If you or someone you know is experiencing suicidal thoughts or behaviors, it is important to seek help immediately. Contact your healthcare provider or a mental health professional for assistance.
  2. If you are taking SSRIs and are experiencing side effects such as akathisia, insomnia, anxiety, or agitation, talk to your healthcare provider about your options. They may be able to adjust your medication or recommend other treatments.
  3. It is important to never take more than the prescribed amount of SSRIs or to combine SSRIs with other medications without first consulting your healthcare provider.

Overall, while SSRIs are a helpful and effective treatment for many mental health conditions, it is important to be aware of the potential risks associated with these medications. By staying informed and seeking help when needed, individuals can reduce their risk of intentional self-harm by poisoning with SSRIs.