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Retrovirus as the cause of diseases classified elsewhere Save


ICD-10 code: B97.3

Chapter: Certain infectious and parasitic diseases

Retrovirus as the cause of diseases classified elsewhere

Retroviruses are a type of virus that use RNA as their genetic material. These viruses are known to cause a variety of diseases, including cancer, immunodeficiency, and neurological disorders. In some cases, retroviruses can cause diseases that are classified elsewhere, which means that the disease is caused by a retrovirus but is not classified as a retroviral disease.

One example of a disease that is caused by a retrovirus but is classified elsewhere is multiple sclerosis (MS). MS is a chronic autoimmune disease that affects the central nervous system. While the exact cause of MS is unknown, researchers have found that a retrovirus called the human endogenous retrovirus type W (HERV-W) may play a role in the development of the disease.

Another example of a disease that is caused by a retrovirus but is classified elsewhere is chronic fatigue syndrome (CFS). CFS is a debilitating condition that is characterized by extreme fatigue that does not improve with rest. While the exact cause of CFS is unknown, researchers have found that a retrovirus called the xenotropic murine leukemia virus-related virus (XMRV) may be involved in the development of the disease.

  1. Retrovirus and Cancer
  2. Retroviruses have been found to cause various types of cancer, including leukemia, lymphoma, and sarcoma. These viruses can insert their genetic material into the DNA of host cells, disrupting normal cell growth and division. Some retroviruses, such as the human T-cell leukemia virus type 1 (HTLV-1), can cause cancer by activating oncogenes or inactivating tumor suppressor genes.

  3. Retrovirus and Immunodeficiency
  4. Retroviruses are also known to cause immunodeficiency, which is a condition that weakens the immune system and makes individuals more susceptible to infections. The most well-known retrovirus that causes immunodeficiency is the human immunodeficiency virus (HIV), which leads to acquired immunodeficiency syndrome (AIDS). HIV infects and destroys CD4+ T cells, which are a type of white blood cell that plays a crucial role in the immune system.

  5. Retrovirus and Neurological Disorders
  6. Retroviruses have also been linked to various neurological disorders, such as Parkinson's disease and amyotrophic lateral sclerosis (ALS). Researchers have found that retroviruses can cause inflammation in the brain and nervous system, leading to the death of nerve cells and the development of neurological symptoms.

Overall, retroviruses are a diverse group of viruses that can cause a wide range of diseases. While some retroviral diseases are well-known, such as HIV/AIDS, others are classified elsewhere and may