Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints. The disease causes inflammation, pain, and stiffness in the joints, eventually leading to damage and loss of function. RA is commonly associated with the presence of rheumatoid factor (RF), an antibody that reacts against the body's own tissues, but there are cases in which patients have RA without RF.
RA without RF is known as seronegative RA and is diagnosed based on the presence of other symptoms and laboratory tests. Patients with seronegative RA may have similar symptoms to those with RF-positive RA, including swelling and tenderness in the joints, morning stiffness, and fatigue.
When it comes to RA affecting the ankle and foot, patients may experience pain, swelling, and stiffness in these areas. The inflammation can cause damage to the joints and surrounding tissues, leading to deformities and difficulties with walking and balance.
It is important to diagnose and treat RA early to prevent joint damage and disability. Treatment usually involves medication to reduce inflammation and pain, as well as physical therapy and lifestyle changes to improve joint function and overall health.
If you are experiencing symptoms of RA, including pain and stiffness in the ankle and foot, it is important to see a doctor for diagnosis and treatment. Early intervention can help slow the progression of the disease and improve quality of life.