Rheumatoid nodules are a common occurrence in individuals suffering from rheumatoid arthritis (RA). These nodules are small, firm lumps that form under the skin. They can appear at different sites throughout the body, and when multiple nodules are present, it is known as rheumatoid nodule, multiple sites.
RA is a chronic autoimmune disease that affects the joints, leading to inflammation, pain, and stiffness. In some cases, it can also affect other parts of the body. Rheumatoid nodules are one of the extra-articular manifestations of RA that affect up to 30% of individuals with the disease. They are more common in individuals who have had RA for a long time and those with more severe forms of the disease.
Rheumatoid nodules usually develop in areas with high friction or pressure, such as the elbows, fingers, and heels. They can also appear in other parts of the body, including the lungs, heart, and eyes. Multiple nodules can form simultaneously, making movement and daily activities challenging for the patient. In some cases, these nodules can also become infected and require medical attention.
The exact cause of rheumatoid nodules is not known, but they are believed to be a result of the immune system's response to the inflammation caused by RA. The nodules are made up of immune cells, fibroblasts, and collagen, and can vary in size, shape, and firmness. They can be painless or tender to the touch, and their appearance can change over time.
In conclusion, rheumatoid nodules are a common extra-articular manifestation of RA that can affect multiple sites throughout the body. They can vary in size, shape, and firmness and can be a source of discomfort and mobility challenges for the patient. If you have RA and notice the development of a nodule or nodules, it is essential to inform your rheumatologist and discuss possible treatment options.