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Toxic effect of trichloroethylene, undetermined Save


ICD-10 code: T53.2X4

Chapter: Injury, poisoning and certain other consequences of external causes

Toxic Effect of Trichloroethylene, Undetermined

Trichloroethylene, also known as TCE, is a colorless liquid that is widely used as a solvent in various industries. The chemical is a potent carcinogen and causes various health hazards. TCE exposure can lead to liver damage, kidney damage, and respiratory problems. However, the toxic effect of trichloroethylene is still undetermined, and researchers are exploring its potential health risks.

Trichloroethylene is a volatile organic compound (VOC) that is often found in groundwater, soil, and air near industrial facilities that use the chemical. Inhalation and skin contact with TCE are the most common routes of exposure. The chemical can also enter the body through drinking contaminated water or consuming contaminated food.

The toxicity of trichloroethylene has been studied extensively, and the chemical has been classified as a human carcinogen by the International Agency for Research on Cancer (IARC). Long-term exposure to TCE is associated with an increased risk of cancer, including liver cancer, kidney cancer, and lymphoma. The chemical can also cause reproductive and developmental effects, including low birth weight, birth defects, and miscarriage.

Despite the well-known health risks associated with trichloroethylene exposure, the toxic effect of the chemical is still undetermined. Scientists are studying the chemical's molecular mechanisms to better understand how it causes toxicity. Recent research has shown that TCE can damage DNA and disrupt cellular processes, leading to cell death and tissue damage.

  1. One study found that TCE exposure caused oxidative stress in the liver, leading to liver damage.
  2. Another study showed that the chemical can cause kidney damage by altering the expression of genes involved in kidney function.
  3. Research has also suggested that trichloroethylene exposure may be linked to autoimmune diseases, such as lupus and rheumatoid arthritis.

The toxic effect of trichloroethylene is still undetermined, but the evidence suggests that the chemical poses significant health risks. It is crucial to limit exposure to TCE in the workplace and the environment to prevent adverse health effects. When handling trichloroethylene, appropriate personal protective equipment should be worn, and exposure should be minimized through engineering controls and ventilation systems.

In conclusion, trichloroethylene is a highly toxic chemical that poses significant health risks. Despite ongoing research, the toxic effect of trichloroethylene is still undetermined. Therefore, it is essential to take all necessary precautions to limit exposure to TCE and protect public health.