Underdosing of predominantly beta-adrenoreceptor agonists Save
ICD-10 code: T44.5X6
Chapter: Injury, poisoning and certain other consequences of external causes
Underdosing of Predominantly Beta-Adrenoreceptor Agonists: Causes and Risks
When it comes to treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), predominantly beta-adrenoreceptor agonists (PBAAs) like salbutamol and terbutaline are often prescribed. These medications work by relaxing the muscles in the airways, making it easier to breathe. However, underdosing of PBAAs can put patients at risk of exacerbations and other complications.
Causes of Underdosing
Underdosing can occur for a variety of reasons. One common cause is poor inhaler technique. Many patients do not use their inhalers correctly, which can result in inadequate dosing. Another cause is failure to adhere to the prescribed treatment regimen. Patients may skip doses or stop taking their medication altogether, which can lead to underdosing.
In some cases, underdosing may be intentional. Patients may try to stretch their medication to save money or avoid side effects. However, this can have serious consequences, as underdosing can lead to worsening of symptoms and increased risk of exacerbations.
Risks of Underdosing
Underdosing of PBAAs can lead to a range of complications, including increased risk of exacerbations, hospitalizations, and even death. Patients may experience worsening of symptoms such as shortness of breath, wheezing, and chest tightness. In severe cases, underdosing can lead to respiratory failure and the need for mechanical ventilation.
Underdosing can also lead to medication overuse. When patients do not receive adequate relief from their symptoms, they may be tempted to use their inhaler more frequently than prescribed. This can lead to a cycle of overuse and underdosing, which can be difficult to break.
Preventing Underdosing
Preventing underdosing requires a multifaceted approach. Healthcare providers must ensure that patients receive proper education on inhaler technique and adherence to treatment regimens. Patients should be encouraged to ask questions and seek clarification if they are unsure about how to use their inhaler or when to take their medication.
Regular follow-up appointments are also important to ensure that patients are receiving adequate relief from their symptoms and to adjust treatment regimens as needed. Healthcare providers should also be aware of the potential for intentional underdosing and work with patients to address any concerns they may have about their medication.
- Ensure proper inhaler technique
- Promote adherence to treatment regimens
- Encourage patient education and communication
- Conduct regular follow-up appointments