Acute and fulminating melioidosis digital illustration

Acute and fulminating melioidosis Save


ICD-10 code: A24.1

Disease category: A24: Glanders and melioidosis

Acute and fulminating melioidosis is a severe infectious disease caused by the bacterium Burkholderia pseudomallei. It is prevalent in Southeast Asia and northern Australia, where it is considered an endemic disease. Melioidosis can present with a variety of symptoms ranging from mild fever to severe sepsis and can affect multiple organs, including the lungs, liver, spleen, and brain. The fulminating form of the disease is a severe and potentially fatal form of melioidosis that can lead to rapid deterioration of the patient's health.

Melioidosis is a soil-borne disease, and infection usually occurs through inhalation of contaminated dust or through direct contact with contaminated soil or water. The incubation period of the disease is usually between 1-21 days, and symptoms may develop gradually or rapidly depending on the severity of the infection.

The symptoms of acute and fulminating melioidosis can be severe and include fever, chills, cough, chest pain, difficulty breathing, confusion, and seizures. The disease can progress rapidly, leading to septic shock and multiple organ failure. Diagnosis is usually made by culturing the bacterium from blood or other bodily fluids.

In severe cases of melioidosis, patients may require intensive care and mechanical ventilation. If the disease has affected multiple organs, surgical intervention may be necessary. Prevention of melioidosis includes wearing protective clothing and avoiding exposure to contaminated soil or water.

In conclusion, acute and fulminating melioidosis is a severe infectious disease that can lead to rapid deterioration of the patient's health. Early diagnosis and prompt treatment with appropriate antibiotics can improve the patient's prognosis. Prevention of melioidosis includes avoiding exposure to contaminated soil or water and wearing protective clothing when handling soil or other potentially contaminated materials.

Treatment of Acute and fulminating melioidosis:

Treatment of acute and fulminating melioidosis requires hospitalization and intravenous antibiotics for at least 10-14 days. The antibiotics used for treating melioidosis include ceftazidime, meropenem, and imipenem. These antibiotics are often used in combination to achieve the best possible outcome.

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