Central pontine myelinolysis digital illustration

Central pontine myelinolysis Save


ICD-10 code: G37.2

Disease category: G37: Other demyelinating diseases of central nervous system

Understanding Central Pontine Myelinolysis

Central pontine myelinolysis (CPM) is a rare neurological disorder that affects the brainstem's myelin sheath, which is responsible for transmitting signals between the brain and the rest of the body. The condition is caused by the rapid correction of sodium levels in the body and is most commonly associated with severe alcoholism, malnutrition, liver disease, and electrolyte imbalances.

CPM can cause a wide range of symptoms, including difficulty speaking and swallowing, muscle weakness, and paralysis. In severe cases, the condition can lead to coma or death. The symptoms of CPM typically develop over a period of several days to a week.

Causes of Central Pontine Myelinolysis

The most common cause of CPM is the rapid correction of hyponatremia (low sodium levels) in the body. This can occur when someone with hyponatremia is given too much sodium too quickly, causing the body to try and compensate for the sudden change in sodium levels. This can lead to the breakdown of the myelin sheath in the brainstem, resulting in CPM.

Other factors that can contribute to the development of CPM include severe alcoholism, liver disease, malnutrition, and electrolyte imbalances. These conditions can cause significant changes in the body's fluid and electrolyte balance, which can lead to the development of CPM.

Diagnosing Central Pontine Myelinolysis

Diagnosing CPM can be challenging, as the symptoms of the condition can be similar to those of other neurological disorders. A doctor may perform a physical exam and order tests, such as a CT scan or MRI, to help diagnose the condition.

The diagnosis of CPM is typically confirmed through the detection of characteristic changes in the brainstem on imaging studies.

Conclusion

Central pontine myelinolysis is a rare neurological disorder that can have serious consequences if left untreated. The condition is most commonly associated with rapid changes in sodium levels in the body and is often seen in individuals with severe alcoholism, malnutrition, and liver disease. If you or someone you know is experiencing symptoms of CPM, it is important to seek medical attention right away.

  1. Understanding Central Pontine Myelinolysis
  2. Causes of Central Pontine Myelinolysis
  3. Diagnosing Central Pontine Myelinolysis

Treatment of Central pontine myelinolysis:

Treatment Options for Central Pontine Myelinolysis

Central pontine myelinolysis (CPM) is a rare neurological disorder that affects the myelin sheath covering nerve fibers in the brain stem. It is often caused by rapid correction of sodium levels in the blood and can lead to severe neurological symptoms such as muscle weakness, paralysis, and coma. While there is no cure for CPM, th...

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