Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission Save

Chronic Myeloid Leukemia, BCR/ABL-positive, Not Having Achieved Remission

Chronic myeloid leukemia (CML) is a type of cancer that affects the blood and bone marrow. It is characterized by the presence of a genetic abnormality called the Philadelphia chromosome, which results in the formation of a fusion gene called BCR/ABL. This gene produces a protein that promotes the growth and survival of cancerous cells.

CML is usually treated with targeted therapies, such as tyrosine kinase inhibitors, which can control the growth of cancerous cells and prolong the life of patients. However, some patients may not achieve remission with these treatments and may require additional therapies or interventions.

Patients with CML who have not achieved remission may experience a range of symptoms, such as fatigue, weakness, fever, and weight loss. They may also have an enlarged spleen, which can cause abdominal pain and discomfort.

1. Regular Monitoring:

Patients who have not achieved remission should undergo regular monitoring to assess the progression of their disease and the effectiveness of their treatment. This may involve blood tests, bone marrow biopsies, and imaging studies.

2. Supportive Care:

Patients may also require supportive care to manage their symptoms and improve their quality of life. This may include medications to control pain and discomfort, nutritional support, and physical therapy.

3. Clinical Trials:

Patients who have not achieved remission may be eligible to participate in clinical trials of new treatments and interventions. These trials can provide access to cutting-edge therapies that are not yet available to the general public.

In conclusion, CML is a complex disease that can be difficult to treat, especially in patients who have not achieved remission. However, with regular monitoring, supportive care, and access to clinical trials, patients can continue to receive the best possible care and improve their prognosis.