Complete androgen insensitivity syndrome Save

Understanding Complete Androgen Insensitivity Syndrome (CAIS)

Complete androgen insensitivity syndrome (CAIS) is a rare genetic condition that affects the development of a person's reproductive system. It is a type of intersex condition that occurs when a person with XY chromosomes is born with a female body and external genitalia.

People with CAIS have a mutation on the androgen receptor gene, which makes their bodies unable to respond to androgens, such as testosterone. As a result, their bodies develop along female lines, despite having XY chromosomes.

Here are some facts about CAIS:

1. CAIS affects about 1 in 20,000 to 1 in 64,000 people who are assigned female at birth.
2. People with CAIS typically have female external genitalia, including a clitoris, labia, and vagina.
3. However, they do not have a uterus or fallopian tubes, and their ovaries are often underdeveloped or absent.
4. Because they do not produce eggs, people with CAIS are infertile and cannot get pregnant.
5. People with CAIS often identify as female and may have a gender identity that aligns with their female appearance.

CAIS is usually diagnosed during puberty, when a person does not start menstruating or develops breast tissue. Doctors may perform a physical exam, blood tests, and imaging tests to confirm the diagnosis.

It's important to note that people with CAIS may face unique challenges related to their reproductive health, identity, and social experiences. They may also require specialized medical care, such as hormone replacement therapy, to maintain their health and well-being.

Overall, CAIS is a complex condition that requires sensitivity, understanding, and support from healthcare providers, loved ones, and society as a whole. By raising awareness about CAIS and promoting inclusion and acceptance, we can help create a more supportive and equitable world for all people.