Drug or chemical induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) Save

Understanding Drug or Chemical Induced Diabetes Mellitus with Hyperosmolarity without Nonketotic Hyperglycemic-Hyperosmolar Coma (NKHHC)

Diabetes Mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to insulin deficiency or insulin resistance. However, certain drugs or chemicals can induce diabetes mellitus, leading to hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC). This condition is a rare form of diabetes mellitus, and it is essential to understand its causes and symptoms to manage it effectively.

1. Causes: Certain drugs or chemicals can induce diabetes mellitus, leading to hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC). These drugs include corticosteroids, thiazides, and antipsychotics, while chemicals such as methanol, ethylene glycol, and iron can also cause this condition. The mechanism behind drug or chemical-induced diabetes mellitus is not well understood, but it is believed to be due to the toxic effect of these substances on pancreatic beta cells, leading to insulin deficiency.
2. Symptoms: The symptoms of drug or chemical-induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) are similar to those of other types of diabetes mellitus. These symptoms include increased thirst, frequent urination, blurred vision, fatigue, and weight loss. However, the absence of nonketotic hyperglycemic-hyperosmolar coma (NKHHC) distinguishes this condition from other forms of diabetes mellitus.
3. Diagnosis: The diagnosis of drug or chemical-induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) is based on clinical symptoms, medical history, and laboratory tests. Blood glucose levels, HbA1c, and urine tests are performed to confirm the diagnosis.
4. Treatment: The treatment of drug or chemical-induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) involves discontinuing the use of the offending drug or chemical. However, in some cases, insulin therapy may be required to manage hyperglycemia. It is essential to monitor blood glucose levels and manage any complications that may arise.

Drug or chemical-induced diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC) is a rare form of diabetes mellitus, and it is essential to understand its causes, symptoms