Fascioliasis digital illustration

Fascioliasis Save


ICD-10 code: B66.3

Disease category: B66: Other fluke infections

Fascioliasis, also known as liver fluke infection, is a parasitic disease caused by the trematode worm Fasciola hepatica or Fasciola gigantica. This disease primarily affects livestock such as sheep and cattle, but humans can also become infected.

Fasciola hepatica is found in many parts of the world, including Europe, Asia, and the Americas, while Fasciola gigantica is found primarily in Asia and Africa. The disease is more common in areas where sheep and cattle are raised and where there is poor sanitation and hygiene.

Transmission of Fascioliasis occurs through ingestion of metacercariae, the infective stage of the parasite, which are found on aquatic plants, such as watercress or on contaminated water. Once ingested, the metacercariae move through the intestinal wall and into the liver, where they develop into adult worms. The adult worms then produce eggs that pass into the bile ducts and exit the body through the feces, which can contaminate the environment and continue the cycle of infection.

Symptoms of Fascioliasis may not appear for several months after infection and can include abdominal pain, nausea, vomiting, diarrhea, and fever. In chronic cases, the infection can lead to damage of the liver, bile ducts, and pancreas, and can cause chronic inflammation, fibrosis, and cirrhosis of the liver.

Diagnosis of Fascioliasis is made by detection of the parasite in stool samples or through imaging studies such as ultrasound or computed tomography (CT) scan.

The treatment for Fascioliasis is usually with a medication called triclabendazole, which kills the adult worms. Other medications such as nitazoxanide, praziquantel, and albendazole have also been used, but triclabendazole is considered the most effective. Supportive care, including treatment for symptoms and management of complications, may also be necessary.

Prevention of Fascioliasis includes good sanitation and hygiene practices, such as washing vegetables and drinking water from safe sources, avoiding contact with contaminated water, and properly cooking meat from infected animals.

In conclusion, Fascioliasis is a parasitic disease caused by Fasciola hepatica or Fasciola gigantica, which affects both animals and humans. It is primarily transmitted through ingestion of metacercariae and can lead to chronic inflammation, fibrosis, and cirrhosis of the liver. Triclabendazole is the treatment of choice, and prevention includes good sanitation and hygiene practices.

Treatment of Fascioliasis:

The primary treatment for fascioliasis is a medication called triclabendazole. This drug is highly effective against Fasciola hepatica and is considered the first-line treatment for the infection. Triclabendazole works by interfering with the parasite's energy metabolism, preventing it from reproducing and ultimately killing it.

In some cases, a combination of drugs may be used to tr...

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