Follicular lymphoma grade I, spleen Save

Follicular Lymphoma Grade I, Spleen

Follicular lymphoma is a type of non-Hodgkin lymphoma that arises from B-cells, a type of white blood cell. It is classified into three grades based on the size and shape of the cancerous cells. Grade I follicular lymphoma is the least aggressive and has the best prognosis. It is characterized by small, uniform cells that form follicles.

The spleen is an organ located in the upper left side of the abdomen, which plays a vital role in the immune system by filtering blood and removing old or damaged blood cells. Follicular lymphoma grade I can involve the spleen and cause enlargement, which can lead to symptoms such as abdominal pain, fullness, and discomfort. However, spleen involvement in grade I follicular lymphoma is less common than in higher grades.

Diagnosis of follicular lymphoma grade I spleen involves a combination of imaging tests, such as CT scans or MRIs, and biopsy of the affected tissue. A pathologist will examine the tissue under a microscope and look for the characteristic features of follicular lymphoma grade I.

1. Small, uniform cells that form follicles
2. Low mitotic rate
3. Expression of certain proteins on the surface of the cells, such as CD20 and CD10

Once a diagnosis is confirmed, further tests may be done to determine the extent of the disease and to stage it. This information is used to develop an individualized treatment plan that takes into account the patient's overall health, age, and other factors.

While there is no cure for follicular lymphoma grade I spleen, treatment options are available to manage the disease and improve quality of life. These may include watchful waiting, which involves monitoring the disease without treatment until symptoms develop, or active treatment such as chemotherapy, radiation therapy, or immunotherapy.

In conclusion, follicular lymphoma grade I spleen is a relatively rare subtype of non-Hodgkin lymphoma that has a good prognosis. Diagnosis involves imaging tests and biopsy of the affected tissue, and treatment options are available to manage the disease and improve quality of life.