Gastrointestinal stromal tumor of small intestine Save

Gastrointestinal Stromal Tumor of Small Intestine

Gastrointestinal stromal tumors (GISTs) are a rare type of cancer that affects the digestive tract, most often the small intestine. They are classified as a type of sarcoma, which is a cancerous tumor that arises from connective tissue, such as muscle, fat, or nerves. GISTs are usually slow-growing and can be benign, or they can be malignant, meaning they spread to other parts of the body.

GISTs are more common in people over the age of 50, and the average age of diagnosis is 65 years old. They are slightly more common in men than in women. GISTs typically start in the muscular wall of the digestive tract. The most common site is the stomach, followed by the small intestine, which accounts for about 20-25% of all GISTs.

The cause of GISTs is unknown, but recent studies suggest that there may be a genetic component to the development of these tumors. Mutations in certain genes, such as KIT and PDGFRA, have been linked to the development of GISTs.

Symptoms of GISTs vary depending on the size and location of the tumor. Common symptoms include abdominal pain, weight loss, nausea, and vomiting. In some cases, the tumor may cause a blockage in the intestine, leading to severe abdominal pain and vomiting.

Diagnosis of GISTs is typically done with imaging tests, such as CT scans and MRI, and sometimes a biopsy may be needed. Treatment options depend on the size and type of the tumor, as well as the patient’s overall health. Surgery is typically the first line of treatment, and chemotherapy and radiation may be used in some cases.

GISTs of the small intestine are a rare type of cancer and it is important to seek medical attention if you are experiencing any of the symptoms described above.