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ICD-10 code: A24.0

Disease category: A24: Glanders and melioidosis

Glanders is a rare bacterial disease caused by the gram-negative bacterium Burkholderia mallei. The bacterium is primarily found in horses, donkeys, and mules, and it can be transmitted to humans through contact with infected animals or contaminated soil or water. Glanders was once a significant threat to both military personnel and civilians, but it is now rare in developed countries due to effective animal control programs and the availability of effective antibiotics.

Symptoms of glanders can range from mild to severe, depending on the route of exposure and the virulence of the strain of bacteria. The incubation period can range from a few days to several months, and symptoms can include fever, fatigue, muscle aches, and headaches. The bacterium can also cause pneumonia, skin lesions, and abscesses, as well as swelling of the lymph nodes and spleen.

There are no vaccines available for glanders in humans, and treatment can be challenging. The bacterium is resistant to many antibiotics, and a prolonged course of antibiotics is usually required. In severe cases, surgery may be necessary to remove infected tissue.

Prevention is the most effective way to control glanders. The disease can be controlled through measures such as vaccination of animals, screening of imported animals, and quarantine of infected animals. Proper hygiene and safety precautions when handling animals or working in environments where the bacterium is present can also reduce the risk of infection.

In conclusion, glanders is a rare but potentially serious bacterial disease that is primarily found in horses and can be transmitted to humans. Although it is rare in developed countries, it is still a concern in many parts of the world. Prevention through vaccination and proper hygiene measures is the most effective way to control the disease, and early diagnosis and treatment are essential for successful outcomes in infected individuals.

Treatment of Glanders:

Glanders is a bacterial infection caused by Burkholderia mallei, a gram-negative bacillus that primarily affects horses, mules, and donkeys. It can also infect humans through contact with infected animals or contaminated materials. The disease is rare but potentially fatal, and there is currently no vaccine available for humans.

Treatment of glanders typically involves a combination of an...

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