Histoplasmosis duboisii digital illustration

Histoplasmosis duboisii Save


ICD-10 code: B39.5

Disease category: B39: Histoplasmosis

Histoplasmosis duboisii is a rare but severe fungal infection caused by the Histoplasma duboisii fungus. This infection is most commonly found in the African continent, particularly in Central and West Africa. The fungus is typically found in soil enriched with bird and bat droppings, and it can cause a range of symptoms, from mild to severe.

Symptoms of Histoplasmosis duboisii can include fever, cough, chest pain, fatigue, weight loss, skin lesions, and swelling of the lymph nodes. These symptoms can appear two to 17 weeks after exposure to the fungus. In severe cases, the infection can spread to other parts of the body, such as the bones, spleen, and liver.

Diagnosis of Histoplasmosis duboisii is typically made through a combination of physical examination, medical history, and laboratory tests. A chest X-ray or CT scan may also be performed to check for lung involvement. Blood tests can be done to detect antibodies to the fungus, and a biopsy of skin lesions or lymph nodes may also be performed.


Preventing Histoplasmosis duboisii can be challenging, as the fungus is common in certain areas and difficult to eradicate. However, there are several steps that can be taken to reduce the risk of infection, including avoiding exposure to areas with large amounts of bird or bat droppings, wearing protective clothing when handling soil or bird droppings, and using proper ventilation when working in enclosed spaces.

In conclusion, Histoplasmosis duboisii is a rare but potentially serious fungal infection that can cause a range of symptoms. Early diagnosis and treatment are essential for a positive outcome, and preventive measures should be taken to reduce the risk of exposure to the fungus.

Treatment of Histoplasmosis duboisii:

The treatment of histoplasmosis duboisii involves antifungal medications. The duration of treatment and choice of medication depends on the severity of the infection and the immune status of the patient. In mild cases, no treatment may be required and the infection may resolve spontaneously.

For more severe infections or in immunocompromised individuals, treatment with antifungal med...

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