Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis digital illustration

Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis Save


ICD-10 code: N06.3

Disease category: N06: Isolated proteinuria with specified morphological lesion

Isolated Proteinuria with Diffuse Mesangial Proliferative Glomerulonephritis

Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis is a kidney disorder characterized by abnormal levels of protein in the urine. This condition occurs when the glomeruli, which are tiny blood vessels in the kidneys responsible for filtering waste and excess fluids, become inflamed and damaged. However, in this article, we will focus on understanding this condition rather than discussing its treatment options.

Symptoms:

  1. Proteinuria: The primary symptom of isolated proteinuria with diffuse mesangial proliferative glomerulonephritis is the presence of excess protein in the urine. This can result in foamy urine or changes in urine color.
  2. Edema: Some individuals may experience swelling in various parts of the body, such as the legs, ankles, or face. This edema occurs due to the impaired kidney function and fluid retention.
  3. High blood pressure: Glomerulonephritis can lead to elevated blood pressure levels, which may cause headaches, dizziness, or shortness of breath.

Causes:

The exact cause of isolated proteinuria with diffuse mesangial proliferative glomerulonephritis is not fully understood. However, certain factors may contribute to its development:

  1. Genetics: Family history plays a role in the predisposition to kidney diseases, including glomerulonephritis.
  2. Infections: In some cases, glomerulonephritis can occur after an infection, such as strep throat or an upper respiratory infection.
  3. Autoimmune disorders: Conditions like lupus or IgA nephropathy can increase the risk of developing glomerulonephritis.
  4. Exposure to toxins: Certain medications, environmental toxins, or illicit drugs may contribute to kidney damage and glomerulonephritis.

Diagnosis:

To diagnose isolated proteinuria with diffuse mesangial proliferative glomerulonephritis, healthcare professionals will perform various tests, including:

  • Urine analysis: This test helps measure the levels of protein and other substances in the urine, providing insights into kidney function.
  • Blood tests: Blood samples can help assess kidney function, identify possible infections, and measure the levels of waste products in the blood.
  • Kidney biopsy: A small sample of kidney tissue is obtained and examined under a microscope

    Treatment of Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis:

    Treatment Options for Isolated Proteinuria with Diffuse Mesangial Proliferative Glomerulonephritis

    Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis (DMGN) is a kidney disorder characterized by abnormal levels of protein in the urine due to inflammation and damage to the glomeruli. Without proper treatment, this condition can lead to more severe kidney pr...

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