Juvenile rheumatoid polyarthritis (seronegative) Save

Juvenile Rheumatoid Polyarthritis (Seronegative): An Overview

Juvenile Rheumatoid Polyarthritis (JRA), also known as Juvenile Idiopathic Arthritis (JIA), is a chronic autoimmune disorder that primarily affects children under the age of 16. There are several subtypes of JRA, one of which is seronegative JRA. In this article, we will explore the key aspects of juvenile rheumatoid polyarthritis (seronegative) and its impact on young patients.

JRA is characterized by chronic joint inflammation, which can lead to pain, stiffness, and limited mobility. Seronegative JRA refers to a specific subtype of JRA in which the blood tests for rheumatoid factor (RF) come back negative. RF is an antibody commonly found in patients with rheumatoid arthritis, but its absence in seronegative JRA distinguishes it from other forms of the disease.

The exact cause of seronegative JRA remains unknown, but research suggests a combination of genetic and environmental factors may contribute to its development. It is important to note that JRA is not a contagious condition and cannot be transmitted from one person to another.

Signs and Symptoms

Seronegative JRA primarily affects the joints, causing pain, swelling, and tenderness. The symptoms may vary from mild to severe, and they can fluctuate over time. Common signs of seronegative JRA include:

1. Joint pain and stiffness, especially in the morning or after periods of inactivity.
2. Swollen and warm joints.
3. Reduced range of motion and difficulty with daily activities.
4. Fatigue and general weakness.

In addition to joint-related symptoms, some children with seronegative JRA may experience systemic symptoms such as fever, rash, and eye inflammation.

Diagnosis and Management

Diagnosing seronegative JRA involves a thorough evaluation of the patient's medical history, physical examination, blood tests, and imaging studies. Since seronegative JRA shares similarities with other forms of JRA, proper diagnosis is crucial for developing an appropriate management plan.

While this article does not cover treatment, it is worth noting that the management of seronegative JRA often involves a multidisciplinary approach. Healthcare professionals, including rheumatologists, physical therapists, and occupational therapists, work together to alleviate symptoms, improve joint function, and enhance the quality of life for children with seronegative JRA.

Conclusion

Seronegative JRA is a subtype of juvenile rheumatoid