Kayser-Fleischer ring, bilateral Save
ICD-10 code: H18.043
Disease category: H18.04: Kayser-Fleischer ring
Kayser-Fleischer Ring, Bilateral: A Distinctive Ocular Finding
The Kayser-Fleischer ring, bilateral, is a distinctive ocular finding that can be observed in individuals suffering from certain medical conditions. This article aims to provide an overview of this intriguing phenomenon, its causes, and its significance.
The Kayser-Fleischer ring, bilateral, is a characteristic brownish or greenish discoloration of the cornea, the transparent front part of the eye. It was first described by two German physicians, Bernhard Kayser and Bruno Fleischer, in the late 19th century. The ring is typically seen in both eyes and appears as a band around the periphery of the cornea.
This ocular abnormality is primarily associated with Wilson's disease, a rare genetic disorder characterized by impaired copper metabolism in the body. In Wilson's disease, excessive copper accumulates in various organs, including the liver, brain, and cornea. The Kayser-Fleischer ring, bilateral, results from copper deposition in Descemet's membrane, a layer of the cornea.
The presence of the Kayser-Fleischer ring, bilateral, serves as an important diagnostic marker for Wilson's disease, especially in individuals with neurological or hepatic symptoms. Physicians often use slit-lamp examination, a specialized microscope, to visualize and confirm the presence of the ring. It is important to note that the absence of the Kayser-Fleischer ring does not exclude the diagnosis of Wilson's disease, as it may not always be present.
In addition to Wilson's disease, the Kayser-Fleischer ring, bilateral, can rarely be observed in other conditions associated with copper metabolism disorders, such as primary biliary cirrhosis and Indian childhood cirrhosis. However, it is crucial to distinguish these conditions from Wilson's disease, as their treatment and prognosis differ significantly.
In conclusion, the Kayser-Fleischer ring, bilateral, is a distinctive ocular finding linked primarily to Wilson's disease. Its identification can aid in the diagnosis of this rare genetic disorder, prompting further evaluation and appropriate management. If you suspect the presence of the Kayser-Fleischer ring, bilateral, or have any concerns about your ocular health, it is essential to consult a healthcare professional for a comprehensive assessment.
- References:
- Brewer GJ. Wilson disease. Medicine. 2005;84(6):337-364. doi:10.1097/01.md.0000180761.52715.c2
- European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Wilson's disease. J Hepatol. 2012;56(3):671-685. doi:10.101
Treatment of Kayser-Fleischer ring, bilateral:
Treatment Options for Kayser-Fleischer Ring, Bilateral
Kayser-Fleischer ring, bilateral, also known as Wilson's disease, is a rare genetic disorder that affects the body's ability to metabolize copper. This condition leads to the accumulation of copper in various organs, including the liver, brain, and eyes. One of the most notable signs of Kayser-Fleischer ring is the presence of ...
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