Lymphocyte depleted Hodgkin lymphoma (LDHL) is a subtype of Hodgkin lymphoma, a cancer that affects the lymphatic system. It is a rare and aggressive form of the disease, accounting for less than 1% of all cases of Hodgkin lymphoma.
LDHL is characterized by the presence of few lymphocytes (a type of white blood cell) in the cancerous tissue. This makes it difficult for the body to mount an effective immune response against the cancer cells. LDHL typically affects older adults, and is more common in men than in women.
When LDHL spreads to the intrapelvic lymph nodes, it can cause a range of symptoms. The intrapelvic lymph nodes are located in the pelvis, between the hip bones. They play a key role in filtering lymph fluid from the lower half of the body.
When LDHL affects the intrapelvic lymph nodes, it can cause pelvic pain, swelling, and discomfort. Patients may also experience urinary problems, such as frequent urination or difficulty urinating. In some cases, bowel movements may also be affected, causing constipation or diarrhea.
Diagnosis of LDHL typically involves a biopsy of the affected tissue. This allows doctors to examine the cancer cells and determine the subtype of Hodgkin lymphoma. Imaging tests, such as CT scans or MRI scans, may also be used to determine the extent of the cancer and identify any areas of spread.
If you are experiencing any symptoms of LDHL, such as pelvic pain or urinary problems, it is important to speak with your doctor. Early diagnosis and treatment can improve the chances of a successful outcome.
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