Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck digital illustration

Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck Save


ICD-10 code: C81.01

Disease category: C81.0: Nodular lymphocyte predominant Hodgkin lymphoma

Nodular Lymphocyte Predominant Hodgkin Lymphoma in Head, Face, and Neck Lymph Nodes

Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a rare type of Hodgkin lymphoma that primarily affects the lymph nodes in the head, face, and neck region. The lymph nodes in this area are also referred to as the cervical lymph nodes. NLPHL accounts for approximately 5% of all Hodgkin lymphoma cases.

Unlike classical Hodgkin lymphoma, NLPHL is characterized by the presence of large, abnormal cells called lymphocytic and histiocytic (L&H) cells. These cells are found in nodules, or small masses, within the lymph nodes. The nodules are surrounded by normal lymphoid tissue, which is why the condition is referred to as nodular lymphocyte predominant Hodgkin lymphoma.

It is important to note that NLPHL is a slow-growing cancer, and the majority of patients experience a good prognosis. However, it is still important to seek proper medical attention and follow-up care to ensure the best outcome.

  1. Symptoms
  2. Swollen lymph nodes in the neck, face, or head
  3. Fever
  4. Night sweats
  5. Unexplained weight loss
  6. Fatigue

It is important to note that these symptoms are not exclusive to NLPHL and may be indicative of other conditions as well. Therefore, it is important to seek medical attention if you experience any of these symptoms.

  1. Diagnosis
  2. Physical exam and medical history
  3. Blood tests to assess overall health and detect any abnormalities
  4. Imaging studies, such as CT scans, PET scans, or MRI, to visualize the lymph nodes and surrounding tissue
  5. Biopsy of the affected lymph node to confirm the diagnosis

Once a diagnosis has been confirmed, additional tests may be conducted to determine the extent of the cancer and develop an appropriate treatment plan.

NLPHL is a rare type of Hodgkin lymphoma that affects the lymph nodes in the head, face, and neck region. It is characterized by the presence of abnormal cells called L&H cells, which are found in nodules within the lymph nodes. While the condition is typically slow-growing and associated with a good prognosis, it is important to seek proper medical attention and follow-up care to ensure the best outcome.

Treatment of Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck:

Treatment Options for Nodular Lymphocyte Predominant Hodgkin Lymphoma in the Head, Face, and Neck
Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) is a rare subtype of Hodgkin Lymphoma that typically affects the lymph nodes in the head, face, and neck. The condition is characterized by the presence of large, abnormal cells called lymphocyte-predominant cells, which can be easil...

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