Other Cushing's syndrome Save

Understanding Other Cushing's Syndrome

When we hear about Cushing's Syndrome, we often think of its most common form, which is caused by the overproduction of the hormone cortisol by the adrenal glands. However, there are other types of Cushing's Syndrome that are less known but equally important to understand.

Other Cushing's Syndrome refers to cases where the excess cortisol production is not caused by an adrenal gland tumor, but by other factors such as a pituitary gland tumor or the use of corticosteroid medications. Here's what you need to know about these less common forms of Cushing's Syndrome:

1. Pituitary Cushing's Syndrome: This form of the disease is caused by a tumor in the pituitary gland, which stimulates the adrenal glands to produce excess cortisol. Pituitary Cushing's Syndrome is the most common type of Other Cushing's Syndrome, accounting for about 70% of cases.
2. Adrenal Cushing's Syndrome: This type of Cushing's Syndrome is caused by a tumor in one or both adrenal glands, which results in the overproduction of cortisol. Adrenal Cushing's Syndrome is less common than Pituitary Cushing's Syndrome, accounting for only 15-20% of cases.
3. Ectopic Cushing's Syndrome: This rare form of the disease is caused by a tumor outside of the pituitary gland or adrenal glands that secretes ACTH, the hormone that stimulates cortisol production. Ectopic Cushing's Syndrome accounts for less than 10% of cases.
4. Iatrogenic Cushing's Syndrome: This type of Cushing's Syndrome is caused by the prolonged use of corticosteroid medications, such as prednisone or dexamethasone. Iatrogenic Cushing's Syndrome is the most common form of the disease in people who do not have a tumor or other medical condition causing the excess cortisol production.

Other Cushing's Syndrome can cause a range of symptoms, such as weight gain, high blood pressure, and muscle weakness. However, the specific symptoms and their severity can vary depending on the underlying cause of the disease.

If you suspect that you may have Cushing's Syndrome, it's important to talk to your healthcare provider. They can perform tests to determine the cause of the excess cortisol production and develop an appropriate treatment plan.