Poisoning by carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics, assault, sequela Save

Poisoning by Carbonic-Anhydrase Inhibitors, Benzothiadiazides, and Other Diuretics, Assault, Sequela

Poisoning by carbonic-anhydrase inhibitors, benzothiadiazides, and other diuretics can cause serious harm to the body. These medications are commonly used to treat hypertension, edema, and other conditions related to fluid retention. However, if taken in excessive amounts or ingested by accident, they can cause severe symptoms and even death.

Assault can also lead to poisoning by diuretics. In cases of intentional overdose, individuals may take large quantities of these medications in an attempt to harm themselves or others. This can be a serious medical emergency, requiring immediate treatment to prevent long-term sequela.

The symptoms of poisoning by diuretics can vary depending on the specific medication involved and the amount ingested. Common symptoms include nausea, vomiting, diarrhea, dizziness, confusion, and seizures. In severe cases, poisoning can lead to coma, respiratory failure, and even death.

1. Carbonic-anhydrase inhibitors: These medications work by blocking the activity of an enzyme called carbonic anhydrase, which is involved in the production of bicarbonate ions. Common carbonic-anhydrase inhibitors include acetazolamide and methazolamide.
2. Benzothiadiazides: These medications work by reducing the amount of sodium and water reabsorbed by the kidneys. Common benzothiadiazides include hydrochlorothiazide and chlorthalidone.
3. Other diuretics: There are many other types of diuretics that can cause poisoning, including loop diuretics (e.g., furosemide), potassium-sparing diuretics (e.g., spironolactone), and osmotic diuretics (e.g., mannitol).

If you suspect that someone has been poisoned by a diuretic medication, it is important to seek medical attention immediately. Treatment may involve administering activated charcoal to absorb the medication, providing supportive care to manage symptoms, and monitoring vital signs to prevent long-term sequela.

In conclusion, poisoning by carbonic-anhydrase inhibitors, benzothiadiazides, and other diuretics can have serious consequences. Whether caused by accidental ingestion or intentional assault, it is important to recognize the symptoms of poisoning and seek immediate medical attention to prevent long-term sequela.