Recurrent and persistent hematuria with diffuse mesangial proliferative glomerulonephritis Save

Recurrent and Persistent Hematuria with Diffuse Mesangial Proliferative Glomerulonephritis

Recurrent and persistent hematuria can be a concerning symptom, particularly when it is associated with a condition known as diffuse mesangial proliferative glomerulonephritis (DMGN). DMGN is a kidney disorder that affects the glomeruli, which are tiny blood vessels responsible for filtering waste and excess fluid from the blood.

When a person has DMGN, the glomeruli become inflamed and swollen, leading to hematuria, or blood in the urine. This condition can be recurrent and persistent, meaning that blood in the urine may appear repeatedly over time.

Although the exact cause of DMGN is not yet fully understood, it is believed to be an immune-mediated disorder. The immune system mistakenly attacks the glomeruli, causing inflammation and abnormal proliferation of the mesangial cells. This proliferation disrupts the normal filtration process, leading to the presence of blood in the urine.

DMGN can affect individuals of all ages, but it is more commonly diagnosed in children and young adults. It may be associated with certain underlying conditions, such as lupus nephritis, IgA nephropathy, or other autoimmune disorders.

Diagnosing DMGN involves a thorough evaluation of the patient's medical history, physical examination, and laboratory tests. A kidney biopsy is often necessary to confirm the diagnosis, as it allows for a detailed examination of the glomeruli under a microscope.

1. Recurrent Hematuria: The presence of blood in the urine may occur intermittently, with episodes of hematuria followed by periods of normalcy.
2. Persistent Hematuria: In some cases, blood in the urine may be present continuously, without any periods of resolution.

It is important to note that this article does not cover the treatment options for recurrent and persistent hematuria with DMGN. If you suspect you or someone you know may have this condition, it is crucial to consult a healthcare professional for a proper diagnosis and appropriate treatment plan.

Overall, recurrent and persistent hematuria associated with diffuse mesangial proliferative glomerulonephritis can be a concerning symptom that requires medical attention. Understanding the underlying causes and seeking appropriate medical care is crucial for managing this condition effectively.